DMCCB Basel Symposium 2026
Covalent Chemistry in Drug Discovery: From Screening to Development
5. February 2026, Biozentrum Basel
DMCCB Basel Symposium
Covalent Chemistry in Drug Discovery:
From Screening to Development
5th February 2026, Biozentrum Basel
10:00
Welcome Coffee and Registration
10.30
Welcome Message and Introduction
Dr. Christoph Sager, Idorsia Pharmaceuticals and Chair of the OC
Session 1 - Chemical Probes for Functional Discovery
Chair: Prof. Sascha Hoogendoorn, University of Geneva
10.45
Prof. Joanna McGouran, Trinity College Dublin
«Chemical tools to study deubiquitinating enzyme activity»
11.20
Prof. Megan Wright, University of Leeds
«Chemical proteomics approaches to identify the targets of anti-infective compounds»
12.00
Lunch Break and Poster Session
Session 2 - Short Talks
Dr. Christoph Sager, Idorsia Pharmaceuticals
13.30
3x 20 Short Talks, selected from submitted abstracts
14.30
Short break
Session 3 - Covalent Chemistry in Drug Design
Prof. Nathalie Grob, ETH Zurich
15.00
Prof. Matthias Gehringer, Eberhard Karls Universität Tübingen
«Covalent Protein Kinase Inhibitors: Unlocking Unconventional Binding Modes and Neglected Targets»
15.35
Prof. Alberto Dal Corso, University of Milan
«Affinity Enhancement of Protein Ligands by Reversible-Covalent Engagement of Lysine Residues»
16.10
Short break
Session 4 - Translating Chemical Biology to Therapeutic Impact
Prof. Dennis Gillingham, University of Basel
16.40
Prof. Stephan A. Sieber, TU Munich
«Chemical strategies to destroy multiresistant bacteria»
17.15
Dr. Andrea Vaupel & Dr. Jeff McKenna, Novartis Basel
«Adventures in covalent targeting of non-Cys residues with applications to KRAS G12D»
17:50
Prizes and closing remarks
Dr. Christoph Sager, chair of the OC
18:10
Aperitif and end of the symposium
